Main Components of the Digestive System

The digestive system consists of the gastrointestinal (GI) tract and accessory organs.

Gastrointestinal Tract (GI Tract)

This is the continuous tube from the mouth to the anus, approximately 30 feet (9 meters) long in adults.

  1. Mouth:

a.     Role: The starting point of digestion.

b.     Processes:

                                               i.     Food is chewed (mechanical digestion) by teeth.

                                             ii.     Saliva from salivary glands contains amylase, an enzyme that starts breaking down carbohydrates (chemical digestion).

c.     Tongue helps in mixing food and forming the bolus (soft mass of chewed food).

  1. Pharynx and Esophagus:

a)     Pharynx: A shared passage for food and air.

b)     Esophagus: A muscular tube that transports the bolus to the stomach through peristalsis (wave-like muscle contractions).

  1. Stomach:

a.     Role: Stores and breaks down food into a semi-liquid form called chyme.

b.     Processes:

                                               i.     Gastric glands secrete hydrochloric acid (HCl) and enzymes like pepsin (breaks down proteins).

                                             ii.     Mucus protects the stomach lining from acid.

c.     Food remains in the stomach for 2-6 hours.

  1. Small Intestine:

a.     Role: Primary site of digestion and nutrient absorption.

b.     Sections:

                                               i.     Duodenum: Receives bile (from the liver) and pancreatic enzymes (from the pancreas) for digestion.

                                             ii.     Jejunum: Absorbs most nutrients.

                                           iii.     Ileum: Absorbs vitamins like B12 and bile salts.

c.     Villi and Microvilli: Finger-like projections increase the surface area for absorption.

  1. Large Intestine (Colon):

a.     Role: Absorbs water and electrolytes; forms and stores feces.

b.     Sections:

                                               i.     Cecum: Receives material from the small intestine.

                                             ii.     Ascending, Transverse, Descending, Sigmoid Colon: Process and compact waste.

                                           iii.     Rectum: Stores feces.

c.     Houses gut microbiota, which help ferment undigested food.

  1. Anus:

a)     Role: Excretes feces from the body through defecation.

b)     Controlled by internal (involuntary) and external (voluntary) anal sphincters.


Accessory Digestive Organs

These organs assist digestion but are not part of the GI tract.

  1. Salivary Glands:

a)     Produce saliva, which contains enzymes and lubricates food.

  1. Liver:

a)     Largest internal organ.

b)     Produces bile, which emulsifies fats, making them easier to digest.

c)     Processes nutrients absorbed in the small intestine.

  1. Gallbladder:

a)     Stores and concentrates bile.

b)     Releases bile into the duodenum via the bile duct.

  1. Pancreas:

a)     Produces digestive enzymes (amylase, lipase, proteases) and bicarbonate to neutralize stomach acid in the duodenum.

b)     Also an endocrine organ, releasing insulin and glucagon to regulate blood sugar.


Processes of Digestion

  1. Ingestion
  2. Intake of food through the mouth.
  3. Propulsion: Movement of food through the digestive tract (e.g., swallowing and peristalsis).
  4. Mechanical Digestion:

a)     Chewing in the mouth.

b)     Churning in the stomach.

c)     Segmentation in the intestines.

  1. Chemical Digestion:

a)     Enzymatic breakdown of macronutrients (carbohydrates, proteins, and fats).

b)     Begins in the mouth and continues through the stomach and small intestine.

  1. Absorption:

a)     Nutrients are absorbed into the bloodstream or lymph through the walls of the small intestine.

b)     Water and electrolytes are absorbed in the large intestine.

  1. Elimination (Defecation):

a)     Removal of indigestible substances and waste products as feces.


Major Digestive Enzymes

Enzyme

Source

Function

Amylase

Saliva, Pancreas

Breaks down carbohydrates into sugars.

Pepsin

Stomach

Breaks down proteins into peptides.

Lipase

Pancreas

Breaks down fats into fatty acids/glycerol.

Trypsin

Pancreas

Continues protein digestion in the small intestine.

Maltase, Lactase

Small Intestine

Break down disaccharides into monosaccharides.


Common Disorders

  1. Acid Reflux (GERD): Stomach acid flows back into the esophagus.
  2. Irritable Bowel Syndrome (IBS): Chronic inflammation of the colon.
  3. Ulcers: Open sores in the stomach or duodenum caused by H. pylori or NSAIDs.
  4. Lactose Intolerance: Inability to digest lactose due to lack of lactase enzyme.
  5. Celiac Disease: Immune reaction to gluten damaging the small intestine.
  6. Constipation/Diarrhea: Problems with stool consistency and frequency.

Fun Facts

  1. The stomach produces 2-3 litters of gastric juice daily.
  2. The small intestine is about 20 feet long but folds to fit inside the abdomen.
  3. Your liver performs over 500 functions, including detoxification and metabolism.

Would you like a deeper dive into any specific aspect, like disorders or dietary tips?